Even though Acne Differin Cream only contains a small amount of the active ingredient, it can cause severe irritation to those with sensitive skin. Only a small amount is needed for each application, and irritation can occur if more than the necessary amount is applied. Differin Cream also can increase the risk of developing severe sunburn, so natural and artificial sun should be avoiding while using this prescription. A stinging sensation can occur directly after applying Acne Differin Cream, and irritation can occur if Differin Cream is applied to the eyes, mouth, or any areas with mucous membranes.
Topical antimicrobial agents are effective in the treatment of inflammatory disease. Benzoyl peroxide is a bactericide and is an excellent first-line medication. The response to this agent is rapid, with improvement noted as early as five days after treatment has begun, but irritation is common. Water-based products, as compared with alcohol based products, when used at low peroxide concentrations (5 to 5 percent) will help to limit this problem and have an efficacy similar to that of other products in this class. Benzoyl peroxide does not induce resistance; when used with topical or oral antibiotics, it protects against the development of this problem.
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